Facing the complexity of neurobiological maturation

Going bedside-to-benchtop, we try to adress neurobiological mechanisms - underlying psychiatric symptoms in humans - in model organisms. Aiming to gain a better understanding of why particular treatment approaches work in humans, we apply experimental designs in model organisms, enabling the study of mechanisms on the cellular level.

If possible, we try to rely on existing data. However, we have readil

Examples of our efforts in reverse translational studies in child and adolescent psychiatry:

• Jarczok MN, Koenig J, Shively CA, Thayer JF. Behavioral depression is associated with increased vagally mediated heart rate variability in adult female cynomolgus monkeys (Macaca fascicularis). Int J Psychophysiol. 2018 131:139-143. DOI: 10.1016/j.ijpsycho.2017.11.004.